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Small-Molecule Ligands as Potential GDNF Family Receptor Agonists

[Image: see text] To find out potential GDNF family receptor α1 (GFRα1) agonists, small molecules were built up by molecular fragments according to the structure-based drug design approach. Molecular docking was used to identify their binding modes to the biological target GFRα1 in GDNF-binding pock...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Ivanova, Larisa, Tammiku-Taul, Jaana, Sidorova, Yulia, Saarma, Mart, Karelson, Mati
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045390/
https://ncbi.nlm.nih.gov/pubmed/30023796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01932
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