A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat

Neuropathic pain caused by nerve damage is a common and severe class of chronic pain. Disease-modifying clinical therapies are needed as current treatments typically provide only symptomatic relief; show varying clinical efficacy; and most have significant adverse effects. One approach is targeting...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Sidorova, Yulia A., Bespalov, Maxim M., Wong, Agnes W., Kambur, Oleg, Jokinen, Viljami, Lilius, Tuomas O., Suleymanova, Ilida, Karelson, Gunnar, Rauhala, Pekka V., Karelson, Mati, Osborne, Peregrine B., Keast, Janet R., Kalso, Eija A., Saarma, Mart
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478727/
https://ncbi.nlm.nih.gov/pubmed/28680400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00365
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