PDGFRA Amplification is Common in Pediatric and Adult High‐Grade Astrocytomas and Identifies a Poor Prognostic Group in IDH1 Mutant Glioblastoma

High‐grade astrocytomas (HGAs), corresponding to World Health Organization grades III (anaplastic astrocytoma) and IV (glioblastoma; GBM), are biologically aggressive, and their molecular classification is increasingly relevant to clinical management. PDGFRA amplification is common in HGAs, although...

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Bibliografische gegevens
Hoofdauteurs: Phillips, Joanna J., Aranda, Derick, Ellison, David W., Judkins, Alexander R., Croul, Sidney E., Brat, Daniel J., Ligon, Keith L., Horbinski, Craig, Venneti, Sriram, Zadeh, Gelareh, Santi, Mariarita, Zhou, Shengmei, Appin, Christina L., Sioletic, Stefano, Sullivan, Lisa M., Martinez‐Lage, Maria, Robinson, Aaron E., Yong, William H., Cloughesy, Timothy, Lai, Albert, Phillips, Heidi S., Marshall, Roxanne, Mueller, Sabine, Haas‐Kogan, Daphne A., Molinaro, Annette M., Perry, Arie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2013
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715570/
https://ncbi.nlm.nih.gov/pubmed/23438035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12043
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