PDGFRA Amplification is Common in Pediatric and Adult High‐Grade Astrocytomas and Identifies a Poor Prognostic Group in IDH1 Mutant Glioblastoma

High‐grade astrocytomas (HGAs), corresponding to World Health Organization grades III (anaplastic astrocytoma) and IV (glioblastoma; GBM), are biologically aggressive, and their molecular classification is increasingly relevant to clinical management. PDGFRA amplification is common in HGAs, although...

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Egile Nagusiak: Phillips, Joanna J., Aranda, Derick, Ellison, David W., Judkins, Alexander R., Croul, Sidney E., Brat, Daniel J., Ligon, Keith L., Horbinski, Craig, Venneti, Sriram, Zadeh, Gelareh, Santi, Mariarita, Zhou, Shengmei, Appin, Christina L., Sioletic, Stefano, Sullivan, Lisa M., Martinez‐Lage, Maria, Robinson, Aaron E., Yong, William H., Cloughesy, Timothy, Lai, Albert, Phillips, Heidi S., Marshall, Roxanne, Mueller, Sabine, Haas‐Kogan, Daphne A., Molinaro, Annette M., Perry, Arie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2013
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715570/
https://ncbi.nlm.nih.gov/pubmed/23438035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12043
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