PDGFRA Amplification is Common in Pediatric and Adult High‐Grade Astrocytomas and Identifies a Poor Prognostic Group in IDH1 Mutant Glioblastoma

High‐grade astrocytomas (HGAs), corresponding to World Health Organization grades III (anaplastic astrocytoma) and IV (glioblastoma; GBM), are biologically aggressive, and their molecular classification is increasingly relevant to clinical management. PDGFRA amplification is common in HGAs, although...

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Główni autorzy: Phillips, Joanna J., Aranda, Derick, Ellison, David W., Judkins, Alexander R., Croul, Sidney E., Brat, Daniel J., Ligon, Keith L., Horbinski, Craig, Venneti, Sriram, Zadeh, Gelareh, Santi, Mariarita, Zhou, Shengmei, Appin, Christina L., Sioletic, Stefano, Sullivan, Lisa M., Martinez‐Lage, Maria, Robinson, Aaron E., Yong, William H., Cloughesy, Timothy, Lai, Albert, Phillips, Heidi S., Marshall, Roxanne, Mueller, Sabine, Haas‐Kogan, Daphne A., Molinaro, Annette M., Perry, Arie
Format: Artigo
Język:Inglês
Wydane: John Wiley and Sons Inc. 2013
Hasła przedmiotowe:
Research Articles
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715570/
https://ncbi.nlm.nih.gov/pubmed/23438035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12043
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