IDH mutant lower grade (WHO Grades II/III) astrocytomas can be stratified for risk by CDKN2A, CDK4 and PDGFRA copy number alterations

In the 2016, WHO classification of tumors of the central nervous system, isocitrate dehydrogenase (IDH) mutation is a main classifier for lower grade astrocytomas and IDH‐mutated astrocytomas is now regarded as a single group with longer survival. However, the molecular and clinical heterogeneity am...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Yang, Rui Ryan, Shi, Zhi‐feng, Zhang, Zhen‐yu, Chan, Aden Ka‐Yin, Aibaidula, Abudumijiti, Wang, Wei‐wei, Kwan, Johnny Sheung Him, Poon, Wai Sang, Chen, Hong, Li, Wen‐cai, Chung, Nellie Yuk‐Fei, Punchhi, Gopika, Chu, William Ching‐Yuen, Chan, Ivan Sik‐Hei, Liu, Xian‐zhi, Mao, Ying, Li, Kay Ka‐Wai, Ng, Ho‐Keung
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018138/
https://ncbi.nlm.nih.gov/pubmed/31733156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12801
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