IDH mutant lower grade (WHO Grades II/III) astrocytomas can be stratified for risk by CDKN2A, CDK4 and PDGFRA copy number alterations

In the 2016, WHO classification of tumors of the central nervous system, isocitrate dehydrogenase (IDH) mutation is a main classifier for lower grade astrocytomas and IDH‐mutated astrocytomas is now regarded as a single group with longer survival. However, the molecular and clinical heterogeneity am...

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Bibliographic Details
Published in:Brain Pathol
Main Authors: Yang, Rui Ryan, Shi, Zhi‐feng, Zhang, Zhen‐yu, Chan, Aden Ka‐Yin, Aibaidula, Abudumijiti, Wang, Wei‐wei, Kwan, Johnny Sheung Him, Poon, Wai Sang, Chen, Hong, Li, Wen‐cai, Chung, Nellie Yuk‐Fei, Punchhi, Gopika, Chu, William Ching‐Yuen, Chan, Ivan Sik‐Hei, Liu, Xian‐zhi, Mao, Ying, Li, Kay Ka‐Wai, Ng, Ho‐Keung
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018138/
https://ncbi.nlm.nih.gov/pubmed/31733156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12801
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