PATH-23. GENOMIC LANDSCAPE OF IDH-MUTANT PRIMARY GLIOBLASTOMAS SHOWS DISTINCT CLINICAL AND MOLECULAR FEATURES AND THAT CDKN2A SHOULD BE SUPPLEMENTED WITH MGMTp AND G-CIMP FOR PRECISE PROGNOSTICATION

There have only been rare studies of IDH-mutant primary glioblastomas (IDH-mutant astrocytoma IV); there were one or two studies on secondary glioblastomas. In a cohort of 70 cases, we conducted clinical analysis, methylation profiling, RNA sequencing, targeted sequencing, and TERTp seqeuncing on av...

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Publicat a:Neuro Oncol
Autors principals: Wong, Queenie Hoi-Wing, Wong, Gabriel Chun-Hei, Chan, Aden Ka-Yin, Poon, Wai Sang, Chan, Danny Tat-Ming, Chen, Hong, Zhang, Zhen-yu, Noushmehr, Houtan, Jones, Chris, Grabovska, Yura, Mackay, Alan, Chow, Chit, Kwan, Johnny Sheung Him, Chung, Nellie Yuk-Fei, Huang, Queenie Junqi, Poon, Manix Fung-Man, Shi, Zhi-feng, Li, Kay Ka-Wai, Ng, Ho-Keung
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Molecular Pathology & Classification
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651265/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.704
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