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TERT PROMOTER MUTATIONS CONTRIBUTE TO PROGNOSTIC SUBGROUPS OF LOWER GRADE ASTROCYTOMAS

BACKGROUND: Recurrent mutations in the promoter region of TERT (telomerase reverse transcriptase) have been found in various cancers including diffuse gliomas. Mutations lead to TERT upregulation and are associated with aggressive clinical behaviour in glioblastomas. However, the prognostic impact o...

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書目詳細資料
Main Authors: Ng, Ho Keung, Chan, Aden, Yao, Yu, Chan, Danny
格式: Artigo
語言:Inglês
出版: Oxford University Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144625/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou209.12
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