FUS-DDIT3 Prevents the Development of Adipocytic Precursors in Liposarcoma by Repressing PPARγ and C/EBPα and Activating eIF4E

Por Pérez-Mancera, Pedro A., Bermejo-Rodríguez, Camino, Sánchez-Martín, Manuel, Abollo-Jiménez, Fernando, Pintado, Belén, Sánchez-García, Isidro
Publicado em 2008

SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia

Por Pearson, Helen B., Perez-Mancera, Pedro A., Dow, Lukas E., Ryan, Andrew, Tennstedt, Pierre, Bogani, Debora, Elsum, Imogen, Greenfield, Andy, Tuveson, David A., Simon, Ronald, Humbert, Patrick O.
Publicado em 2011

Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence

Por Sadaie, Mahito, Salama, Rafik, Carroll, Thomas, Tomimatsu, Kosuke, Chandra, Tamir, Young, Andrew R.J., Narita, Masako, Pérez-Mancera, Pedro A., Bennett, Dorothy C., Chong, Heung, Kimura, Hiroshi, Narita, Masashi
Publicado em 2013

BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model

Por Perna, Daniele, Karreth, Florian A., Rust, Alistair G., Perez-Mancera, Pedro A., Rashid, Mamunur, Iorio, Francesco, Alifrangis, Constantine, Arends, Mark J., Bosenberg, Marcus W., Bollag, Gideon, Tuveson, David A., Adams, David J.
Publicado no Proc Natl Acad Sci U S A (2015)

STAG2 is a clinically relevant tumor suppressor in pancreatic ductal adenocarcinoma

Por Evers, Lisa, Perez-Mancera, Pedro A, Lenkiewicz, Elizabeth, Tang, Nanyun, Aust, Daniela, Knösel, Thomas, Rümmele, Petra, Holley, Tara, Kassner, Michelle, Aziz, Meraj, Ramanathan, Ramesh K, Von Hoff, Daniel D, Yin, Holly, Pilarsky, Christian, Barrett, Michael T
Publicado em 2014

Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53

Por Kirschner, Kristina, Samarajiwa, Shamith A., Cairns, Jonathan M., Menon, Suraj, Pérez-Mancera, Pedro A., Tomimatsu, Kosuke, Bermejo-Rodriguez, Camino, Ito, Yoko, Chandra, Tamir, Narita, Masako, Lyons, Scott K., Lynch, Andy G., Kimura, Hiroshi, Ohbayashi, Tetsuya, Tavaré, Simon, Narita, Masashi
Publicado no PLoS Genet (2015)

Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors

Por Ireland, Lucy, Santos, Almudena, Ahmed, Muhammad S., Rainer, Carolyn, Nielsen, Sebastian R., Quaranta, Valeria, Weyer-Czernilofsky, Ulrike, Engle, Danielle D., Perez-Mancera, Pedro A., Coupland, Sarah E., Taktak, Azzam, Bogenrieder, Thomas, Tuveson, David A., Campbell, Fiona, Schmid, Michael C., Mielgo, Ainhoa
Publicado no Cancer Res (2016)

In vivo identification of tumor suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma

Por Karreth, Florian A., Tay, Yvonne, Perna, Daniele, Ala, Ugo, Tan, Shen Mynn, Rust, Alistair G., DeNicola, Gina, Webster, Kaitlyn A., Weiss, Dror, Perez-Mancera, Pedro A., Krauthammer, Michael, Halaban, Ruth, Provero, Paolo, Adams, David J., Tuveson, David A., Pandolfi, Pier Paolo
Publicado em 2011

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium

Por Holland, Daniel G, Burleigh, Angela, Git, Anna, Goldgraben, Mae A, Perez-Mancera, Pedro A, Chin, Suet-Feung, Hurtado, Antonio, Bruna, Alejandra, Ali, H Raza, Greenwood, Wendy, Dunning, Mark J, Samarajiwa, Shamith, Menon, Suraj, Rueda, Oscar M, Lynch, Andy G, McKinney, Steven, Ellis, Ian O, Eaves, Connie J, Carroll, Jason S, Curtis, Christina, Aparicio, Samuel, Caldas, Carlos
Publicado em 2011

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

Por Pérez-Mancera, Pedro A., Rust, Alistair G., van der Weyden, Louise, Kristiansen, Glen, Li, Allen, Sarver, Aaron L., Silverstein, Kevin A. T., Grützmann, Robert, Aust, Daniela, Rümmele, Petra, Knösel, Thomas, Herd, Colin, Stemple, Derek L., Kettleborough, Ross, Brosnan, Jacqueline A., Li, Ang, Morgan, Richard, Knight, Spencer, Yu, Jun, Stegeman, Shane, Collier, Lara S., ten Hoeve, Jelle J., de Ridder, Jeroen, Klein, Alison P., Goggins, Michael, Hruban, Ralph H., Chang, David K., Biankin, Andrew V., Grimmond, Sean M., Wessels, Lodewyk F. A., Wood, Stephen A., Iacobuzio-Donahue, Christine A., Pilarsky, Christian, Largaespada, David A., Adams, David J., Tuveson, David A.
Publicado em 2012

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

Por Varela, Ignacio, Tarpey, Patrick, Raine, Keiran, Huang, Dachuan, Ong, Choon Kiat, Stephens, Philip, Davies, Helen, Jones, David, Lin, Meng-Lay, Teague, Jon, Bignell, Graham, Butler, Adam, Cho, Juok, Dalgliesh, Gillian L., Galappaththige, Danushka, Greenman, Chris, Hardy, Claire, Jia, Mingming, Latimer, Calli, Lau, King Wai, Marshall, John, McLaren, Stuart, Menzies, Andrew, Mudie, Laura, Stebbings, Lucy, Largaespada, David A., Wessels, L.F.A., Richard, Stephane, Kahnoski, Richard J, Anema, John, Tuveson, David A., Perez-Mancera, Pedro A., Mustonen, Ville, Fischer, Andrej, Adams, David J., Rust, Alistair, Chan-on, Waraporn, Subimerb, Chutima, Dykema, Karl, Furge, Kyle, Campbell, Peter J., Teh, Bin Tean, Stratton, Michael R., Futreal, P. Andrew
Publicado em 2011

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Por Biankin, Andrew V., Waddell, Nicola, Kassahn, Karin S., Gingras, Marie-Claude, Muthuswamy, Lakshmi B., Johns, Amber L., Miller, David K., Wilson, Peter J., Patch, Ann-Marie, Wu, Jianmin, Chang, David K., Cowley, Mark J., Gardiner, Brooke B., Song, Sarah, Harliwong, Ivon, Idrisoglu, Senel, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Wani, Shivangi, Gongora, Milena, Pajic, Marina, Scarlett, Christopher J., Gill, Anthony J., Pinho, Andreia V., Rooman, Ilse, Anderson, Matthew, Holmes, Oliver, Leonard, Conrad, Taylor, Darrin, Wood, Scott, Xu, Qinying, Nones, Katia, Fink, J. Lynn, Christ, Angelika, Bruxner, Tim, Cloonan, Nicole, Kolle, Gabriel, Newell, Felicity, Pinese, Mark, Mead, R. Scott, Humphris, Jeremy L., Kaplan, Warren, Jones, Marc D., Colvin, Emily K., Nagrial, Adnan M., Humphrey, Emily S., Chou, Angela, Chin, Venessa T., Chantrill, Lorraine A., Mawson, Amanda, Samra, Jaswinder S., Kench, James G., Lovell, Jessica A., Daly, Roger J., Merrett, Neil D., Toon, Christopher, Epari, Krishna, Nguyen, Nam Q., Barbour, Andrew, Zeps, Nikolajs, Kakkar, Nipun, Zhao, Fengmei, Wu, Yuan Qing, Wang, Min, Muzny, Donna M., Fisher, William E., Brunicardi, F. Charles, Hodges, Sally E., Reid, Jeffrey G., Drummond, Jennifer, Chang, Kyle, Han, Yi, Lewis, Lora R., Dinh, Huyen, Buhay, Christian J., Beck, Timothy, Timms, Lee, Sam, Michelle, Begley, Kimberly, Brown, Andrew, Pai, Deepa, Panchal, Ami, Buchner, Nicholas, De Borja, Richard, Denroche, Robert E., Yung, Christina K., Serra, Stefano, Onetto, Nicole, Mukhopadhyay, Debabrata, Tsao, Ming-Sound, Shaw, Patricia A., Petersen, Gloria M., Gallinger, Steven, Hruban, Ralph H., Maitra, Anirban, Iacobuzio-Donahue, Christine A., Schulick, Richard D., Wolfgang, Christopher L., Morgan, Richard A., Lawlor, Rita T., Capelli, Paola, Corbo, Vincenzo, Scardoni, Maria, Tortora, Giampaolo, Tempero, Margaret A., Mann, Karen M., Jenkins, Nancy A., Perez-Mancera, Pedro A., Adams, David J., Largaespada, David A., Wessels, Lodewyk F. A., Rust, Alistair G., Stein, Lincoln D., Tuveson, David A., Copeland, Neal G., Musgrove, Elizabeth A., Scarpa, Aldo, Eshleman, James R., Hudson, Thomas J., Sutherland, Robert L., Wheeler, David A., Pearson, John V., McPherson, John D., Gibbs, Richard A., Grimmond, Sean M.
Publicado em 2012