Detection of the novel SARS-CoV-2 European lineage B.1.177 in Ontario, Canada

по Guthrie, Jennifer L., Teatero, Sarah, Zittermann, Sandra, Chen, Yao, Sullivan, Ashleigh, Rilkoff, Heather, Joshi, Esha, Sivaraman, Karthikeyan, de Borja, Richard, Sundaravadanam, Yogi, Laszloffy, Michael, Heisler, Lawrence, Allen, Vanessa G., Simpson, Jared T., Fittipaldi, Nahuel
Опубликовано в: Journal of Clinical Virology Plus (2021)

Cellular and molecular architecture of hematopoietic stem cells and progenitors in genetic models of bone marrow failure

по Heidemann, Stephanie, Bursic, Brian, Zandi, Sasan, Li, Hongbing, Abelson, Sagi, Klaassen, Robert J., Abish, Sharon, Rayar, Meera, Breakey, Vicky R., Moshiri, Houtan, Dhanraj, Santhosh, de Borja, Richard, Shlien, Adam, Dick, John E., Dror, Yigal
Опубликовано в: JCI Insight (2020)

Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair

по Hodel, Karl P, de Borja, Richard, Henninger, Erin E, Campbell, Brittany B, Ungerleider, Nathan, Light, Nicholas, Wu, Tong, LeCompte, Kimberly G, Goksenin, A Yasemin, Bunnell, Bruce A, Tabori, Uri, Shlien, Adam, Pursell, Zachary F
Опубликовано в: eLife (2018)

TMOD-10. REPLICATION REPAIR DEFICIENT MOUSE MODELS PROVIDE INSIGHT ON HYPERMUTANT BRAIN TUMOURS AND COMBINATIONAL IMMUNOTHERAPY

по Galati, Melissa, Bridge, Taylor, Sudhaman, Sumedha, Elshaer, Dana, Ercan, Ayse, Joksimovic, Lazar, Gams, Miki, Hodel, Karl, Lipman, Tatiana, Siddiqui, Iram, de Borja, Richard, Forster, Victoria, Martin, Alberto, Bouffet, Eric, Shlien, Adam, Guidos, Cynthia, Pursell, Zachary, Hawkins, Cynthia, Tabori, Uri
Опубликовано в: Neuro Oncol (2019)

GE-09 COMBINED HEREDITARY AND SOMATIC MUTATIONS OF REPLICATION ERROR REPAIR GENES RESULT IN RAPID ONSET OF ULTRA-HYPERMUTATED MALIGNANT BRAIN TUMORS IN CHILDREN

по Shlien, Adam, Campbell, Brittany B., de Borja, Richard, Alexandrov, Ludmil B., Merino, Diana M., Remke, Marc, Bakry, Doua, Dirks, Peter, Huang, Annie, Grundy, Richard G., Durno, Carol, Aronson, Melyssa, Taylor, Michael D., Pursell, Zachary F., Pearson, Christopher E., Malkin, David, Bouffet, Eric, Hawkins, Cynthia, Campbell, Peter J., Tabori, Uri
Опубликовано в: Neuro Oncol (2015)

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants

по Peltekova, Vanya D, Lemire, Mathieu, Qazi, Aamer M, Zaidi, Syed H E, Trinh, Quang M, Bielecki, Ryszard, Rogers, Marianne, Hodgson, Lyndsey, Wang, Mike, D’Souza, David J A, Zandi, Sasan, Chong, Taryne, Kwan, Jennifer Y Y, Kozak, Krystian, De Borja, Richard, Timms, Lee, Rangrej, Jagadish, Volar, Milica, Chan-Seng-Yue, Michelle, Beck, Timothy, Ash, Colleen, Lee, Shawna, Wang, Jianxin, Boutros, Paul C, Stein, Lincoln D, Dick, John E, Gryfe, Robert, McPherson, John D, Zanke, Brent W, Pollett, Aaron, Gallinger, Steven, Hudson, Thomas J
Опубликовано 2014

Cancers from novel Pole mutant mouse models provide insights into polymerase-mediated hypermutagenesis and immune checkpoint blockade

по Galati, Melissa A., Hodel, Karl P., Gams, Miki S., Sudhaman, Sumedha, Bridge, Taylor, Zahurancik, Walter J., Ungerleider, Nathan A., Park, Vivian S., Ercan, Ayse B., Joksimovic, Lazar, Siddiqui, Iram, Siddaway, Robert, Edwards, Melissa, de Borja, Richard, Elshaer, Dana, Chung, Jiil, Forster, Victoria J., Nunes, Nuno M., Aronson, Melyssa, Wang, Xia, Ramdas, Jagadeesh, Seeley, Andrea, Sarosiek, Tomasz, Dunn, Gavin P., Byrd, Jonathan N., Mordechai, Oz, Durno, Carol, Martin, Alberto, Shlien, Adam, Bouffet, Eric, Suo, Zucai, Jackson, James G., Hawkins, Cynthia E., Guidos, Cynthia J., Pursell, Zachary F., Tabori, Uri
Опубликовано в: Cancer Res (2020)

HG-53 HYPERMUTATION AND NEOANTIGEN FORMATION PREDICT RESPONSE TO IMMUNE CHECKPOINT INHIBITION IN CHILDHOOD BIALLELIC MISMATCH REPAIR DEFICIENT GLIOBLASTOMA

по Campbell, Brittany, Bouffet, Eric, Larouche, Valerie, Mason, Gary, Reddy, Alyssa, Osborn, Michael, Magimairan, Vanan, Merico, Daniele, de Borja, Richard, Chung, Brian, Galati, Melissa, Aronson, Melyssa, Durno, Carol, Kruger, Joerg, Cabric, Vanja, Zhukova, Nataliya, Ramaswamy, Vijay, Farah, Roula, Afzal, Samina, Yalon, Michal, Rechavi, Gideon, Walsh, Michael F., Constantini, Shlomi, Dvir, Rina, Elhasid, Ronit, Sullivan, Michael, Hansford, Jordan R., Dodgshun, Andrew, Klauber-Demore, Nancy, Peterson, Lindsay, Patel, Sunil, Lindhorst, Scott, Atkinson, Jeffrey, Laframboise, Rachel, Cohen, Zane, Dirks, Peter, Taylor, Michael, Malkin, David, Albrecht, Steffen, Dudley, Roy, Jabado, Nada, Hawkins, Cynthia, Shlien, Adam, Tabori, Uri
Опубликовано в: Neuro Oncol (2016)

Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors

по Anderson, Nathaniel D, de Borja, Richard, Young, Matthew D, Fuligni, Fabio, Rosic, Andrej, Roberts, Nicola D, Hajjar, Simon, Layeghifard, Mehdi, Novokmet, Ana, Kowalski, Paul E, Anaka, Matthew, Davidson, Scott, Zarrei, Mehdi, Said, Badr Id, Schreiner, L. Christine, Marchand, Remi, Sitter, Joseph, Gogkoz, Nalan, Brunga, Ledia, Graham, Garrett T, Fullam, Anthony, Pillay, Nischalan, Toretsky, Jeffrey A, Yoshida, Akihiko, Shibata, Tatsuhiro, Metzler, Markus, Somers, Gino R, Scherer, Stephen W, Flanagan, Adrienne M, Campbell, Peter J, Schiffman, Joshua D, Shago, Mary, Alexandrov, Ludmil B, Wunder, Jay S, Andrulis, Irene L, Malkin, David, Behjati, Sam, Shlien, Adam
Опубликовано в: Science (2018)

BPG: Seamless, automated and interactive visualization of scientific data

по P’ng, Christine, Green, Jeffrey, Chong, Lauren C., Waggott, Daryl, Prokopec, Stephenie D., Shamsi, Mehrdad, Nguyen, Francis, Mak, Denise Y. F., Lam, Felix, Albuquerque, Marco A., Wu, Ying, Jung, Esther H., Starmans, Maud H. W., Chan-Seng-Yue, Michelle A., Yao, Cindy Q., Liang, Bianca, Lalonde, Emilie, Haider, Syed, Simone, Nicole A., Sendorek, Dorota, Chu, Kenneth C., Moon, Nathalie C., Fox, Natalie S., Grzadkowski, Michal R., Harding, Nicholas J., Fung, Clement, Murdoch, Amanda R., Houlahan, Kathleen E., Wang, Jianxin, Garcia, David R., de Borja, Richard, Sun, Ren X., Lin, Xihui, Chen, Gregory M., Lu, Aileen, Shiah, Yu-Jia, Zia, Amin, Kearns, Ryan, Boutros, Paul C.
Опубликовано в: BMC Bioinformatics (2019)

Comprehensive Analysis of Hypermutation in Human Cancer

по Campbell, Brittany B., Light, Nicholas, Fabrizio, David, Zatzman, Matthew, Fuligni, Fabio, de Borja, Richard, Davidson, Scott, Edwards, Melissa, Elvin, Julia A., Hodel, Karl P., Zahurancik, Walter J., Suo, Zucai, Lipman, Tatiana, Wimmer, Katharina, Kratz, Christian P., Bowers, Daniel C., Laetsch, Theodore W., Dunn, Gavin P., Johanns, Tanner M., Grimmer, Matthew R., Smirnov, Ivan V., Larouche, Valérie, Samuel, David, Bronsema, Annika, Osborn, Michael, Stearns, Duncan, Raman, Pichai, Cole, Kristina A., Storm, Phillip B., Yalon, Michal, Opocher, Enrico, Mason, Gary, Thomas, Gregory A., Sabel, Magnus, George, Ben, Ziegler, David S., Lindhorst, Scott, Issai, Vanan Magimairajan, Constantini, Shlomi, Toledano, Helen, Elhasid, Ronit, Farah, Roula, Dvir, Rina, Dirks, Peter, Huang, Annie, Galati, Melissa A., Chung, Jiil, Ramaswamy, Vijay, Irwin, Meredith S., Aronson, Melyssa, Durno, Carol, Taylor, Michael D., Rechavi, Gideon, Maris, John M., Bouffet, Eric, Hawkins, Cynthia, Costello, Joseph F., Meyn, M. Stephen, Pursell, Zachary F., Malkin, David, Tabori, Uri, Shlien, Adam
Опубликовано в: Cell (2017)

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

по Biankin, Andrew V., Waddell, Nicola, Kassahn, Karin S., Gingras, Marie-Claude, Muthuswamy, Lakshmi B., Johns, Amber L., Miller, David K., Wilson, Peter J., Patch, Ann-Marie, Wu, Jianmin, Chang, David K., Cowley, Mark J., Gardiner, Brooke B., Song, Sarah, Harliwong, Ivon, Idrisoglu, Senel, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Wani, Shivangi, Gongora, Milena, Pajic, Marina, Scarlett, Christopher J., Gill, Anthony J., Pinho, Andreia V., Rooman, Ilse, Anderson, Matthew, Holmes, Oliver, Leonard, Conrad, Taylor, Darrin, Wood, Scott, Xu, Qinying, Nones, Katia, Fink, J. Lynn, Christ, Angelika, Bruxner, Tim, Cloonan, Nicole, Kolle, Gabriel, Newell, Felicity, Pinese, Mark, Mead, R. Scott, Humphris, Jeremy L., Kaplan, Warren, Jones, Marc D., Colvin, Emily K., Nagrial, Adnan M., Humphrey, Emily S., Chou, Angela, Chin, Venessa T., Chantrill, Lorraine A., Mawson, Amanda, Samra, Jaswinder S., Kench, James G., Lovell, Jessica A., Daly, Roger J., Merrett, Neil D., Toon, Christopher, Epari, Krishna, Nguyen, Nam Q., Barbour, Andrew, Zeps, Nikolajs, Kakkar, Nipun, Zhao, Fengmei, Wu, Yuan Qing, Wang, Min, Muzny, Donna M., Fisher, William E., Brunicardi, F. Charles, Hodges, Sally E., Reid, Jeffrey G., Drummond, Jennifer, Chang, Kyle, Han, Yi, Lewis, Lora R., Dinh, Huyen, Buhay, Christian J., Beck, Timothy, Timms, Lee, Sam, Michelle, Begley, Kimberly, Brown, Andrew, Pai, Deepa, Panchal, Ami, Buchner, Nicholas, De Borja, Richard, Denroche, Robert E., Yung, Christina K., Serra, Stefano, Onetto, Nicole, Mukhopadhyay, Debabrata, Tsao, Ming-Sound, Shaw, Patricia A., Petersen, Gloria M., Gallinger, Steven, Hruban, Ralph H., Maitra, Anirban, Iacobuzio-Donahue, Christine A., Schulick, Richard D., Wolfgang, Christopher L., Morgan, Richard A., Lawlor, Rita T., Capelli, Paola, Corbo, Vincenzo, Scardoni, Maria, Tortora, Giampaolo, Tempero, Margaret A., Mann, Karen M., Jenkins, Nancy A., Perez-Mancera, Pedro A., Adams, David J., Largaespada, David A., Wessels, Lodewyk F. A., Rust, Alistair G., Stein, Lincoln D., Tuveson, David A., Copeland, Neal G., Musgrove, Elizabeth A., Scarpa, Aldo, Eshleman, James R., Hudson, Thomas J., Sutherland, Robert L., Wheeler, David A., Pearson, John V., McPherson, John D., Gibbs, Richard A., Grimmond, Sean M.
Опубликовано 2012