Comprehensive Analysis of Hypermutation in Human Cancer

We present an extensive assessment of mutation burden through sequencing analysis of >81,000 tumors from pediatric and adult patients, including tumors with hypermutation caused by chemotherapy, carcinogens, or germline alterations. Hypermutation was detected in tumor types not previously associa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Campbell, Brittany B., Light, Nicholas, Fabrizio, David, Zatzman, Matthew, Fuligni, Fabio, de Borja, Richard, Davidson, Scott, Edwards, Melissa, Elvin, Julia A., Hodel, Karl P., Zahurancik, Walter J., Suo, Zucai, Lipman, Tatiana, Wimmer, Katharina, Kratz, Christian P., Bowers, Daniel C., Laetsch, Theodore W., Dunn, Gavin P., Johanns, Tanner M., Grimmer, Matthew R., Smirnov, Ivan V., Larouche, Valérie, Samuel, David, Bronsema, Annika, Osborn, Michael, Stearns, Duncan, Raman, Pichai, Cole, Kristina A., Storm, Phillip B., Yalon, Michal, Opocher, Enrico, Mason, Gary, Thomas, Gregory A., Sabel, Magnus, George, Ben, Ziegler, David S., Lindhorst, Scott, Issai, Vanan Magimairajan, Constantini, Shlomi, Toledano, Helen, Elhasid, Ronit, Farah, Roula, Dvir, Rina, Dirks, Peter, Huang, Annie, Galati, Melissa A., Chung, Jiil, Ramaswamy, Vijay, Irwin, Meredith S., Aronson, Melyssa, Durno, Carol, Taylor, Michael D., Rechavi, Gideon, Maris, John M., Bouffet, Eric, Hawkins, Cynthia, Costello, Joseph F., Meyn, M. Stephen, Pursell, Zachary F., Malkin, David, Tabori, Uri, Shlien, Adam
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849393/
https://ncbi.nlm.nih.gov/pubmed/29056344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.048
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