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Targeting Epigenetic Pathways in the Treatment of Pediatric Diffuse (High Grade) Gliomas

Progress in the treatment of adult high-grade gliomas (HGG), including chemoradiation with concurrent and adjuvant temozolomide for glioblastoma, has not translated into significant therapeutic advances for pediatric HGG, where overall survival has plateaued at 15% to 20%, especially when considerin...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Main Authors: Vanan, Magimairajan Issai, Underhill, D. Alan, Eisenstat, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398987/
https://ncbi.nlm.nih.gov/pubmed/28233220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-017-0514-2
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