Hexokinase 2 as oncotarget

di Patra, Krushna C., Hay, Nissim
Pubblicazione 2013

The pentose phosphate pathway and cancer

di Patra, Krushna C., Hay, Nissim
Pubblicato in Trends Biochem Sci (2014)

Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm

di Patra, Krushna C, Bardeesy, Nabeel, Mizukami, Yusuke
Pubblicato in Clin Transl Gastroenterol (2017)

Selective eradication of cancer displaying hyperactive Akt by exploiting the metabolic consequences of Akt activation

di Nogueira, Veronique, Patra, Krushna C, Hay, Nissim
Pubblicato in eLife (2018)

Systemic Akt1 deletion after tumor onset in p53(−/−) mice increases lifespan and regresses thymic lymphoma emulating p53 restoration

di Yu, Wan-Ni, Nogueira, Veronique, Sobhakumari, Arya, Patra, Krushna C., Bhaskar, Prashanth T., Hay, Nissim
Pubblicato in Cell Rep (2015)

mTORC1 Hyperactivity Inhibits Serum Deprivation-Induced Apoptosis via Increased Hexokinase II and GLUT1 Expression, Sustained Mcl-1 Expression, and Glycogen Synthase Kinase 3β Inhi...

di Bhaskar, Prashanth T., Nogueira, Veronique, Patra, Krushna C., Jeon, Sang-Min, Park, Youngkyu, Robey, R. Brooks, Hay, Nissim
Pubblicazione 2009

BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of β-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis

di Vilfranc, Chrystelle L, Che, Li-Xiao, Patra, Krushna C, Niu, Liang, Olowokure, Olugbenga, Wang, Jiang, Shah, Shimul A, Du, Chun-Ying
Pubblicato in World J Hepatol (2021)

Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

di DeWaal, Dannielle, Nogueira, Veronique, Terry, Alexander R., Patra, Krushna C., Jeon, Sang-Min, Guzman, Grace, Au, Jennifer, Long, Christopher P., Antoniewicz, Maciek R., Hay, Nissim
Pubblicato in Nat Commun (2018)

Author Correction: Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

di DeWaal, Dannielle, Nogueira, Veronique, Terry, Alexander R., Patra, Krushna C., Jeon, Sang-Min, Guzman, Grace, Au, Jennifer, Long, Christopher P., Antoniewicz, Maciek R., Hay, Nissim
Pubblicato in Nat Commun (2018)

DDB2 Suppresses Epithelial to Mesenchymal Transition in Colon Cancer

di Roy, Nilotpal, Bommi, Prashant V., Bhat, Uppoor G., Bhattacharjee, Shaumick, Elangovan, Indira, Li, Jing, Patra, Krushna C., Kopanja, Dragana, Blunier, Adam, Benya, Richard, Bagchi, Srilata, Raychaudhuri, Pradip
Pubblicazione 2013

Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer

di Patra, Krushna C., Wang, Qi, Bhaskar, Prashanth T., Miller, Luke, Wang, Zebin, Wheaton, Will, Chandel, Navdeep, Laakso, Markku, Muller, William J., Allen, Eric L., Jha, Abhishek K., Smolen, Gromoslaw A., Clasquin, Michelle F., Robey, Brooks, Hay, Nissim
Pubblicazione 2013

Mutant GNAS drives pancreatic tumorigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism

di Patra, Krushna C., Kato, Yasutaka, Mizukami, Yusuke, Widholz, Sebastian, Boukhali, Myriam, Revenco, Iulia, Grossman, Elizabeth A., Ji, Fei, Sadreyev, Ruslan I., Liss, Andrew S., Screaton, Robert A., Sakamoto, Kei, Ryan, David P., Mino-Kenudson, Mari, Castillo, Carlos Fernandez-del, Nomura, Daniel K., Haas, Wilhelm, Bardeesy, Nabeel
Pubblicato in Nat Cell Biol (2018)

TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion-positive intrahepatic cholangiocarcinoma

di Goyal, Lipika, Shi, Lei, Liu, Leah Y., de la Cruz, Ferran Fece, Lennerz, Jochen K., Raghavan, Srivatsan, Leschiner, Ignaty, Elagina, Liudmila, Siravegna, Giulia, Ng, Raymond W.S., Vu, Phuong, Patra, Krushna C., Saha, Supriya K., Uppot, Raul N., Arellano, Ron, Reyes, Stephanie, Sagara, Takeshi, Otsuki, Sachie, Nadres, Brandon, Shahzade, Heather A., Dey-Guha, Ipsita, Fetter, Isobel J., Baiev, Islam, Van Seventer, Emily E., Murphy, Janet E., Ferrone, Cristina R., Tanabe, Kenneth K., Deshpande, Vikram, Harding, James J., Yaeger, Rona, Kelley, Robin K., Bardelli, Alberto, Iafrate, A. John, Hahn, William C., Benes, Cyril H., Ting, David T., Hirai, Hiroshi, Getz, Gad, Juric, Dejan, Zhu, Andrew X., Corcoran, Ryan B., Bardeesy, Nabeel
Pubblicato in Cancer Discov (2019)