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The pentose phosphate pathway and cancer

The pentose phosphate pathway (PPP), which branches from glycolysis at the first committed step of glucose metabolism, is required for the synthesis of ribonucleotides and is a major source of NADPH. NADPH is required for and consumed during fatty acid synthesis and the scavenging of reactive oxygen...

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Detalles Bibliográficos
Publicado en:Trends Biochem Sci
Main Authors: Patra, Krushna C., Hay, Nissim
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329227/
https://ncbi.nlm.nih.gov/pubmed/25037503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2014.06.005
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