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The pentose phosphate pathway and cancer
The pentose phosphate pathway (PPP), which branches from glycolysis at the first committed step of glucose metabolism, is required for the synthesis of ribonucleotides and is a major source of NADPH. NADPH is required for and consumed during fatty acid synthesis and the scavenging of reactive oxygen...
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| Udgivet i: | Trends Biochem Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329227/ https://ncbi.nlm.nih.gov/pubmed/25037503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2014.06.005 |
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