Hexokinase 2 as oncotarget

Por Patra, Krushna C., Hay, Nissim
Publicado em 2013

The pentose phosphate pathway and cancer

Por Patra, Krushna C., Hay, Nissim
Publicado no Trends Biochem Sci (2014)

Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm

Por Patra, Krushna C, Bardeesy, Nabeel, Mizukami, Yusuke
Publicado no Clin Transl Gastroenterol (2017)

Selective eradication of cancer displaying hyperactive Akt by exploiting the metabolic consequences of Akt activation

Por Nogueira, Veronique, Patra, Krushna C, Hay, Nissim
Publicado no eLife (2018)

Systemic Akt1 deletion after tumor onset in p53(−/−) mice increases lifespan and regresses thymic lymphoma emulating p53 restoration

Por Yu, Wan-Ni, Nogueira, Veronique, Sobhakumari, Arya, Patra, Krushna C., Bhaskar, Prashanth T., Hay, Nissim
Publicado no Cell Rep (2015)

mTORC1 Hyperactivity Inhibits Serum Deprivation-Induced Apoptosis via Increased Hexokinase II and GLUT1 Expression, Sustained Mcl-1 Expression, and Glycogen Synthase Kinase 3β Inhi...

Por Bhaskar, Prashanth T., Nogueira, Veronique, Patra, Krushna C., Jeon, Sang-Min, Park, Youngkyu, Robey, R. Brooks, Hay, Nissim
Publicado em 2009

Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

Por DeWaal, Dannielle, Nogueira, Veronique, Terry, Alexander R., Patra, Krushna C., Jeon, Sang-Min, Guzman, Grace, Au, Jennifer, Long, Christopher P., Antoniewicz, Maciek R., Hay, Nissim
Publicado no Nat Commun (2018)

Author Correction: Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

Por DeWaal, Dannielle, Nogueira, Veronique, Terry, Alexander R., Patra, Krushna C., Jeon, Sang-Min, Guzman, Grace, Au, Jennifer, Long, Christopher P., Antoniewicz, Maciek R., Hay, Nissim
Publicado no Nat Commun (2018)

DDB2 Suppresses Epithelial to Mesenchymal Transition in Colon Cancer

Por Roy, Nilotpal, Bommi, Prashant V., Bhat, Uppoor G., Bhattacharjee, Shaumick, Elangovan, Indira, Li, Jing, Patra, Krushna C., Kopanja, Dragana, Blunier, Adam, Benya, Richard, Bagchi, Srilata, Raychaudhuri, Pradip
Publicado em 2013

Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer

Por Patra, Krushna C., Wang, Qi, Bhaskar, Prashanth T., Miller, Luke, Wang, Zebin, Wheaton, Will, Chandel, Navdeep, Laakso, Markku, Muller, William J., Allen, Eric L., Jha, Abhishek K., Smolen, Gromoslaw A., Clasquin, Michelle F., Robey, Brooks, Hay, Nissim
Publicado em 2013

Mutant GNAS drives pancreatic tumorigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism

Por Patra, Krushna C., Kato, Yasutaka, Mizukami, Yusuke, Widholz, Sebastian, Boukhali, Myriam, Revenco, Iulia, Grossman, Elizabeth A., Ji, Fei, Sadreyev, Ruslan I., Liss, Andrew S., Screaton, Robert A., Sakamoto, Kei, Ryan, David P., Mino-Kenudson, Mari, Castillo, Carlos Fernandez-del, Nomura, Daniel K., Haas, Wilhelm, Bardeesy, Nabeel
Publicado no Nat Cell Biol (2018)

TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion-positive intrahepatic cholangiocarcinoma

Por Goyal, Lipika, Shi, Lei, Liu, Leah Y., de la Cruz, Ferran Fece, Lennerz, Jochen K., Raghavan, Srivatsan, Leschiner, Ignaty, Elagina, Liudmila, Siravegna, Giulia, Ng, Raymond W.S., Vu, Phuong, Patra, Krushna C., Saha, Supriya K., Uppot, Raul N., Arellano, Ron, Reyes, Stephanie, Sagara, Takeshi, Otsuki, Sachie, Nadres, Brandon, Shahzade, Heather A., Dey-Guha, Ipsita, Fetter, Isobel J., Baiev, Islam, Van Seventer, Emily E., Murphy, Janet E., Ferrone, Cristina R., Tanabe, Kenneth K., Deshpande, Vikram, Harding, James J., Yaeger, Rona, Kelley, Robin K., Bardelli, Alberto, Iafrate, A. John, Hahn, William C., Benes, Cyril H., Ting, David T., Hirai, Hiroshi, Getz, Gad, Juric, Dejan, Zhu, Andrew X., Corcoran, Ryan B., Bardeesy, Nabeel
Publicado no Cancer Discov (2019)