Selective eradication of cancer displaying hyperactive Akt by exploiting the metabolic consequences of Akt activation

Lignende værker

• Systemic Akt1 Deletion after Tumor Onset in p53−/− Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration
  af: Wan-Ni Yu, et al.
  Udgivet: (2015-07-01)
• Systemic Akt1 deletion after tumor onset in p53(−/−) mice increases lifespan and regresses thymic lymphoma emulating p53 restoration
  af: Yu, Wan-Ni, et al.
  Udgivet: (2015)
• Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
  af: Hay, Nissim
  Udgivet: (2016)
• Is Akt the “Warburg kinase”?—Akt-energy metabolism interactions and oncogenesis
  af: Robey, R. Brooks, et al.
  Udgivet: (2008)
• mTORC1 Hyperactivity Inhibits Serum Deprivation-Induced Apoptosis via Increased Hexokinase II and GLUT1 Expression, Sustained Mcl-1 Expression, and Glycogen Synthase Kinase 3β Inhibition
  af: Bhaskar, Prashanth T., et al.
  Udgivet: (2009)