Hexokinase 2 as oncotarget

Autor Patra, Krushna C., Hay, Nissim
Vydáno 2013

The pentose phosphate pathway and cancer

Autor Patra, Krushna C., Hay, Nissim
Vydáno v Trends Biochem Sci (2014)

Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm

Autor Patra, Krushna C, Bardeesy, Nabeel, Mizukami, Yusuke
Vydáno v Clin Transl Gastroenterol (2017)

Selective eradication of cancer displaying hyperactive Akt by exploiting the metabolic consequences of Akt activation

Autor Nogueira, Veronique, Patra, Krushna C, Hay, Nissim
Vydáno v eLife (2018)

Systemic Akt1 deletion after tumor onset in p53(−/−) mice increases lifespan and regresses thymic lymphoma emulating p53 restoration

Autor Yu, Wan-Ni, Nogueira, Veronique, Sobhakumari, Arya, Patra, Krushna C., Bhaskar, Prashanth T., Hay, Nissim
Vydáno v Cell Rep (2015)

mTORC1 Hyperactivity Inhibits Serum Deprivation-Induced Apoptosis via Increased Hexokinase II and GLUT1 Expression, Sustained Mcl-1 Expression, and Glycogen Synthase Kinase 3β Inhi...

Autor Bhaskar, Prashanth T., Nogueira, Veronique, Patra, Krushna C., Jeon, Sang-Min, Park, Youngkyu, Robey, R. Brooks, Hay, Nissim
Vydáno 2009

BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of β-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis

Autor Vilfranc, Chrystelle L, Che, Li-Xiao, Patra, Krushna C, Niu, Liang, Olowokure, Olugbenga, Wang, Jiang, Shah, Shimul A, Du, Chun-Ying
Vydáno v World J Hepatol (2021)

Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

Autor DeWaal, Dannielle, Nogueira, Veronique, Terry, Alexander R., Patra, Krushna C., Jeon, Sang-Min, Guzman, Grace, Au, Jennifer, Long, Christopher P., Antoniewicz, Maciek R., Hay, Nissim
Vydáno v Nat Commun (2018)

Author Correction: Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

Autor DeWaal, Dannielle, Nogueira, Veronique, Terry, Alexander R., Patra, Krushna C., Jeon, Sang-Min, Guzman, Grace, Au, Jennifer, Long, Christopher P., Antoniewicz, Maciek R., Hay, Nissim
Vydáno v Nat Commun (2018)

DDB2 Suppresses Epithelial to Mesenchymal Transition in Colon Cancer

Autor Roy, Nilotpal, Bommi, Prashant V., Bhat, Uppoor G., Bhattacharjee, Shaumick, Elangovan, Indira, Li, Jing, Patra, Krushna C., Kopanja, Dragana, Blunier, Adam, Benya, Richard, Bagchi, Srilata, Raychaudhuri, Pradip
Vydáno 2013

Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer

Autor Patra, Krushna C., Wang, Qi, Bhaskar, Prashanth T., Miller, Luke, Wang, Zebin, Wheaton, Will, Chandel, Navdeep, Laakso, Markku, Muller, William J., Allen, Eric L., Jha, Abhishek K., Smolen, Gromoslaw A., Clasquin, Michelle F., Robey, Brooks, Hay, Nissim
Vydáno 2013

Mutant GNAS drives pancreatic tumorigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism

Autor Patra, Krushna C., Kato, Yasutaka, Mizukami, Yusuke, Widholz, Sebastian, Boukhali, Myriam, Revenco, Iulia, Grossman, Elizabeth A., Ji, Fei, Sadreyev, Ruslan I., Liss, Andrew S., Screaton, Robert A., Sakamoto, Kei, Ryan, David P., Mino-Kenudson, Mari, Castillo, Carlos Fernandez-del, Nomura, Daniel K., Haas, Wilhelm, Bardeesy, Nabeel
Vydáno v Nat Cell Biol (2018)

TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion-positive intrahepatic cholangiocarcinoma

Autor Goyal, Lipika, Shi, Lei, Liu, Leah Y., de la Cruz, Ferran Fece, Lennerz, Jochen K., Raghavan, Srivatsan, Leschiner, Ignaty, Elagina, Liudmila, Siravegna, Giulia, Ng, Raymond W.S., Vu, Phuong, Patra, Krushna C., Saha, Supriya K., Uppot, Raul N., Arellano, Ron, Reyes, Stephanie, Sagara, Takeshi, Otsuki, Sachie, Nadres, Brandon, Shahzade, Heather A., Dey-Guha, Ipsita, Fetter, Isobel J., Baiev, Islam, Van Seventer, Emily E., Murphy, Janet E., Ferrone, Cristina R., Tanabe, Kenneth K., Deshpande, Vikram, Harding, James J., Yaeger, Rona, Kelley, Robin K., Bardelli, Alberto, Iafrate, A. John, Hahn, William C., Benes, Cyril H., Ting, David T., Hirai, Hiroshi, Getz, Gad, Juric, Dejan, Zhu, Andrew X., Corcoran, Ryan B., Bardeesy, Nabeel
Vydáno v Cancer Discov (2019)