Population pharmacokinetic studies in pediatrics: Issues in design and analysis

Por Meibohm, Bernd, Läer, Stephanie, Panetta, John C., Barrett, Jeffrey S.
Publicado em 2005

Mathematical Modelling of Folate Metabolism

Por Panetta, John C., Paugh, Steven W., Evans, William E.
Publicado em 2013

Pharmacokinetics, Immunogenicity, and Safety of Weekly Dosing of Brentuximab in Pediatric Patients with Hodgkin Lymphoma

Por Flerlage, Jamie, Metzger, Monika, Wu, Jianrong, Panetta, John C
Publicado no Cancer Chemother Pharmacol (2016)

Genetic Predictors of Interindividual Variability in Hepatic CYP3A4 Expression

Por Lamba, Vishal, Panetta, John C., Strom, Stephen, Schuetz, Erin G.
Publicado em 2010

Using plasma topotecan pharmacokinetics to estimate topotecan exposure in cerebrospinal fluid of children with medulloblastoma

Por Freeman, Burgess B., Iacono, Lisa C., Panetta, John C., Gajjar, Amar, Stewart, Clinton F.
Publicado em 2006

Modeling Mechanisms of In Vivo Variability in Methotrexate Accumulation and Folate Pathway Inhibition in Acute Lymphoblastic Leukemia Cells

Por Panetta, John C., Sparreboom, Alex, Pui, Ching-Hon, Relling, Mary V., Evans, William E.
Publicado em 2010

Hypersensitivity Reaction to High-Dose Methotrexate and Successful Rechallenge in a Pediatric Patient with Osteosarcoma

Por Scott, Jeffrey R., Ward, Deborah A., Crews, Kristine R., Panetta, John C., Navid, Fariba
Publicado no Pediatr Blood Cancer (2013)

Sorafenib Metabolism, Transport, and Enterohepatic Recycling: Physiologically Based Modeling and Simulation in Mice

Por Edginton, Andrea N., Zimmerman, Eric I., Vasilyeva, Aksana, Baker, Sharyn D., Panetta, John C.
Publicado no Cancer Chemother Pharmacol (2016)

Population PK/PD Model of Homocysteine Concentrations after High-Dose Methotrexate Treatment in Patients with Acute Lymphoblastic Leukemia

Por Rühs, Hauke, Becker, Achim, Drescher, Anne, Panetta, John C., Pui, Ching-Hon, Relling, Mary V., Jaehde, Ulrich
Publicado em 2012

Gene expression and thioguanine nucleotide disposition in acute lymphoblastic leukemia after in vivo mercaptopurine treatment

Por Zaza, Gianluigi, Cheok, Meyling, Yang, Wenjian, Panetta, John C., Pui, Ching-Hon, Relling, Mary V., Evans, William E.
Publicado em 2005

Clinical Pharmacokinetics of Amifostine and WR1065 in Pediatric Patients with Medulloblastoma

Por McKibbin, Trevor, Panetta, John C., Fouladi, Maryam, Gajjar, Amar, Bai, Feng, Okcu, M. Fatih, Stewart, Clinton F.
Publicado em 2010

Application of a Highly Specific and Sensitive Fluorescent HPLC Method for Topotecan Lactone in Whole Blood

Por Hubbard, K. Elaine, Schaiquevich, Paula, Bai, Feng, Fraga, Charles H., Miller, Laura, Panetta, John C., Stewart, Clinton F.
Publicado em 2009

Formalizing an integrative, multidisciplinary cancer therapy discovery workflow

Por McGuire, Mary F., Enderling, Heiko, Wallace, Dorothy I., Batra, Jaspreet, Jordan, Marie, Kumar, Sushil, Panetta, John C., Pasquier, Eddy
Publicado em 2013

Phase I Study of the Tolerability and Pharmacokinetics of Palifermin in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Por Srinivasan, Ashok, Kasow, Kimberly A., Cross, Shane, Parrish, Melissa, Wang, Chong, Srivastava, Deo K., Cai, Xiangjun, Panetta, John C., Leung, Wing
Publicado em 2012

Mechanisms of Dexamethasone-Induced Disturbed Sleep and Fatigue in Paediatric Patients Receiving Treatment for ALL

Por Vallance, Kelly, Liu, Wei, Mandrell, Belinda N., Panetta, John C, Gattuso, Jami S., Hockenberry, Marilyn, Zupanec, Sue, Yang, Lei, Yang, Jie, Hinds, Pamela S.
Publicado em 2010

Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics

Por Cheok, Meyling, Yang, Wenjian, Zaza, Gianluigi, Cheng, Qing, Panetta, John C., Pui, Ching-Hon, Downing, James R., Relling, Mary V., Evans, William E.
Publicado em 2005

Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics

Por Kager, Leo, Cheok, Meyling, Yang, Wenjian, Zaza, Gianluigi, Cheng, Qing, Panetta, John C., Pui, Ching-Hon, Downing, James R., Relling, Mary V., Evans, William E.
Publicado em 2005

Compartment-specific roles of ABC transporters define differential topotecan distribution in brain parenchyma and cerebrospinal fluid

Por Shen, Jun, Carcaboso, Angel M., Hubbard, K. Elaine, Tagen, Michael, Wynn, Henry G., Panetta, John C., Waters, Christopher M., Elmeliegy, Mohamed A., Stewart, Clinton F.
Publicado em 2009

P-glycoprotein, but not Multidrug Resistance Protein 4, Plays a Role in the Systemic Clearance of Irinotecan and SN-38 in Mice

Por Tagen, Michael, Zhuang, Yanli, Zhang, Fan, Harstead, K. Elaine, Shen, Jun, Schaiquevich, Paula, Fraga, Charles H., Panetta, John C., Waters, Christopher M., Stewart, Clinton F.
Publicado no Drug Metab Lett (2010)

Population Pharmacokinetics of Oral Topotecan in Infants and Very Young Children with Brain Tumors Demonstrates a Role of ABCG2 rs4148157 on the Absorption Rate Constant

Por Roberts, Jessica K., Birg, Anna V., Lin, Tong, Daryani, Vinay M., Panetta, John C., Broniscer, Alberto, Robinson, Giles W., Gajjar, Amar J., Stewart, Clinton F.
Publicado no Drug Metab Dispos (2016)