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Clinical Pharmacokinetics of Amifostine and WR1065 in Pediatric Patients with Medulloblastoma

PURPOSE: We evaluated the pharmacokinetics of amifostine and WR1065 in pediatric patients with newly diagnosed medulloblastoma, to assess the influence of patient covariates, including demographics, clinical characteristics, and genetic polymorphisms, on amifostine and WR1065 pharmacokinetic paramet...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McKibbin, Trevor, Panetta, John C., Fouladi, Maryam, Gajjar, Amar, Bai, Feng, Okcu, M. Fatih, Stewart, Clinton F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818675/
https://ncbi.nlm.nih.gov/pubmed/20103669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1997
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