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Clinical Pharmacokinetics of Amifostine and WR1065 in Pediatric Patients with Medulloblastoma

PURPOSE: We evaluated the pharmacokinetics of amifostine and WR1065 in pediatric patients with newly diagnosed medulloblastoma, to assess the influence of patient covariates, including demographics, clinical characteristics, and genetic polymorphisms, on amifostine and WR1065 pharmacokinetic paramet...

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Detalhes bibliográficos
Main Authors: McKibbin, Trevor, Panetta, John C., Fouladi, Maryam, Gajjar, Amar, Bai, Feng, Okcu, M. Fatih, Stewart, Clinton F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818675/
https://ncbi.nlm.nih.gov/pubmed/20103669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1997
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