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Clinical Pharmacokinetics of Amifostine and WR1065 in Pediatric Patients with Medulloblastoma

PURPOSE: We evaluated the pharmacokinetics of amifostine and WR1065 in pediatric patients with newly diagnosed medulloblastoma, to assess the influence of patient covariates, including demographics, clinical characteristics, and genetic polymorphisms, on amifostine and WR1065 pharmacokinetic paramet...

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Hlavní autoři: McKibbin, Trevor, Panetta, John C., Fouladi, Maryam, Gajjar, Amar, Bai, Feng, Okcu, M. Fatih, Stewart, Clinton F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818675/
https://ncbi.nlm.nih.gov/pubmed/20103669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1997
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