Amifostine Protects Against Cisplatin-Induced Ototoxicity in Children with Average-Risk Medulloblastoma

PURPOSE: To determine the role of amifostine as a protectant against cisplatin-induced ototoxicity in patients with average risk (AR) medulloblastoma treated with craniospinal radiotherapy and 4 cycles of cisplatin-based dose-intense chemotherapy and stem cell rescue. PATIENTS AND METHODS: The prima...

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Main Authors: Fouladi, Maryam, Chintagumpala, Murali, Ashley, David, Kellie, Stewart, Gururangan, Sridharan, Hassall, Tim, Gronewold, Lindsey, Stewart, Clinton F, Wallace, Dana, Broniscer, Alberto, Hale, Gregory A., Kasow, Kimberly A., Merchant, Thomas E., Morris, Brannon, Krasin, Mathew, Kun, Larry E., Boyett, James M., Gajjar, Amar
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504739/
https://ncbi.nlm.nih.gov/pubmed/18669462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.14.3974
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