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Application of a Highly Specific and Sensitive Fluorescent HPLC Method for Topotecan Lactone in Whole Blood
Individualization of topotecan dosing reduces inter-patient variability in topotecan exposure, presumably reducing toxicity and increasing efficacy. However, logistical limitations (e.g., requirement for plasma, intensive bedside plasma processing) have prevented widespread application of this appro...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914494/ https://ncbi.nlm.nih.gov/pubmed/19277971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.1173 |
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