Subconjunctival Carboplatin and Systemic Topotecan Treatment in Preclinical Models of Retinoblastoma

BACKGROUND: We previously showed that the combination of topotecan (TPT) and carboplatin (CBP) is more effective than current chemotherapeutic combinations used to treat retinoblastoma in an orthotopic xenograft model. However, systemic coadministration of these agents is not ideal, because both cau...

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Bibliographic Details
Main Authors: Nemeth, Katie M., Federico, Sara, Carcaboso, Angel Montero, Shen, Ying, Schaiquevich, Paula, Zhang, Jiakun, Egorin, Merrill, Stewart, Clinton, Dyer, Michael A.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000447/
https://ncbi.nlm.nih.gov/pubmed/20818652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25574
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