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Suprachoroidal Injection of Topotecan for Retinoblastoma: A Preclinical Study

Purpose: To assess whether levels of topotecan that are expected to be therapeutic against retinoblastoma tumors can be achieved within the retina and choroid by suprachoroidal injection (SCI) and to assess toxicity and safety in vivo. Design: Pharmacokinetics and dose escalation toxicity study. Sub...

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Huvudupphov: Arun D. Singh, MD, Vishal Raval, MD, Sandeep Kumar, PhD, Anthony Daniels, MD
Materialtyp: Artigo
Språk:Inglês
Utgiven: Elsevier 2025-11-01
Serie:Ophthalmology Science
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Länkar:http://www.sciencedirect.com/science/article/pii/S2666914525001733
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