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Fluorescence Detection of the Anticancer Drug Topotecan in Plasma and Whole Blood by Two-Photon Excitation

The anticancer drug topotecan was detected in human plasma and whole blood using two-photon excitation at 730 or 820 nm. These wavelengths are longer than the main absorption bands of hemoglobin. Two-photon excitation of topotecan was demonstrated by a quadratic dependence of the emission intensity...

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Publicat a:Anal Biochem
Autors principals: Burke, Thomas G., Malak, Henryk, Gryczynski, Ignacy, Mi, Zihou, Lakowicz, Joseph R.
Format: Artigo
Idioma:Inglês
Publicat: 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915068/
https://ncbi.nlm.nih.gov/pubmed/8937572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1006/abio.1996.0463
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