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Hypersensitivity Reaction to High-Dose Methotrexate and Successful Rechallenge in a Pediatric Patient with Osteosarcoma

Hypersensitivity reactions to methotrexate are rare, but have been reported. Methotrexate has shown activity against many malignancies, and omission of methotrexate therapy may increase the risk of cancer-related death in some patients. Therefore, rechallenging patients with methotrexate following h...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Scott, Jeffrey R., Ward, Deborah A., Crews, Kristine R., Panetta, John C., Navid, Fariba
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267721/
https://ncbi.nlm.nih.gov/pubmed/23955991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24741
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