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Phase I Study of the Tolerability and Pharmacokinetics of Palifermin in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

The maximum tolerated dose of palifermin, a keratinocyte growth factor, in children is not known, and its pharmacokinetics in this population has not been well studied. This is a phase I study of palifermin was designed to evaluate its tolerability at doses of 40, 60, and 90 μg/kg/day in children ag...

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Detalhes bibliográficos
Main Authors: Srinivasan, Ashok, Kasow, Kimberly A., Cross, Shane, Parrish, Melissa, Wang, Chong, Srivastava, Deo K., Cai, Xiangjun, Panetta, John C., Leung, Wing
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539307/
https://ncbi.nlm.nih.gov/pubmed/22542710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2012.04.013
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