Pharmacokinetics and Pharmacodynamics of Treosulfan in Patients With Thalassemia Major Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

A treosulfan (Treo)-based conditioning regimen prior to hematopoietic stem cell transplantation (HSCT) has been successfully used in treating hematological malignant and nonmalignant diseases. We report Treo pharmacokinetics (PK) in patients with thalassemia major undergoing HSCT (n = 87), receiving...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Mohanan, Ezhilpavai, Panetta, John C., Lakshmi, Kavitha M., Edison, Eunice S., Korula, Anu, NA, Fouzia, Abraham, Aby, Viswabandya, Auro, George, Biju, Mathews, Vikram, Srivastava, Alok, Balasubramanian, Poonkuzhali
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045930/
https://ncbi.nlm.nih.gov/pubmed/29247522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.988
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