Pharmacokinetics and Pharmacodynamics of Treosulfan in Patients With Thalassemia Major Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

A treosulfan (Treo)-based conditioning regimen prior to hematopoietic stem cell transplantation (HSCT) has been successfully used in treating hematological malignant and nonmalignant diseases. We report Treo pharmacokinetics (PK) in patients with thalassemia major undergoing HSCT (n = 87), receiving...

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Bibliographic Details
Published in:Clin Pharmacol Ther
Main Authors: Mohanan, Ezhilpavai, Panetta, John C., Lakshmi, Kavitha M., Edison, Eunice S., Korula, Anu, NA, Fouzia, Abraham, Aby, Viswabandya, Auro, George, Biju, Mathews, Vikram, Srivastava, Alok, Balasubramanian, Poonkuzhali
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045930/
https://ncbi.nlm.nih.gov/pubmed/29247522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.988
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