Pharmacokinetics and Pharmacodynamics of Treosulfan in Patients With Thalassemia Major Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

A treosulfan (Treo)-based conditioning regimen prior to hematopoietic stem cell transplantation (HSCT) has been successfully used in treating hematological malignant and nonmalignant diseases. We report Treo pharmacokinetics (PK) in patients with thalassemia major undergoing HSCT (n = 87), receiving...

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Vydáno v:Clin Pharmacol Ther
Hlavní autoři: Mohanan, Ezhilpavai, Panetta, John C., Lakshmi, Kavitha M., Edison, Eunice S., Korula, Anu, NA, Fouzia, Abraham, Aby, Viswabandya, Auro, George, Biju, Mathews, Vikram, Srivastava, Alok, Balasubramanian, Poonkuzhali
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045930/
https://ncbi.nlm.nih.gov/pubmed/29247522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.988
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