Pharmacokinetics and Pharmacodynamics of Treosulfan in Patients With Thalassemia Major Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

A treosulfan (Treo)-based conditioning regimen prior to hematopoietic stem cell transplantation (HSCT) has been successfully used in treating hematological malignant and nonmalignant diseases. We report Treo pharmacokinetics (PK) in patients with thalassemia major undergoing HSCT (n = 87), receiving...

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Опубликовано в: :Clin Pharmacol Ther
Главные авторы: Mohanan, Ezhilpavai, Panetta, John C., Lakshmi, Kavitha M., Edison, Eunice S., Korula, Anu, NA, Fouzia, Abraham, Aby, Viswabandya, Auro, George, Biju, Mathews, Vikram, Srivastava, Alok, Balasubramanian, Poonkuzhali
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6045930/
https://ncbi.nlm.nih.gov/pubmed/29247522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.988
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