Intrinsic Novobiocin Resistance in Staphylococcus saprophyticus

Por Vickers, Anna A., Chopra, Ian, O'Neill, Alex J.
Publicado em 2007

Increased Mutability of Staphylococci in Biofilms as a Consequence of Oxidative Stress

Por Ryder, Victoria J., Chopra, Ian, O’Neill, Alex J.
Publicado em 2012

Staphylococcus aureus Biofilms Promote Horizontal Transfer of Antibiotic Resistance

Por Savage, Victoria J., Chopra, Ian, O'Neill, Alex J.
Publicado em 2013

Population Diversification in Staphylococcus aureus Biofilms May Promote Dissemination and Persistence

Por Savage, Victoria J., Chopra, Ian, O’Neill, Alex J.
Publicado em 2013

Mutagenesis Mapping of the Protein-Protein Interaction Underlying FusB-Type Fusidic Acid Resistance

Por Cox, Georgina, Edwards, Thomas A., O'Neill, Alex J.
Publicado em 2013

In Vitro Studies Indicate a High Resistance Potential for the Lantibiotic Nisin in Staphylococcus aureus and Define a Genetic Basis for Nisin Resistance

Por Blake, Katy L., Randall, Chris P., O'Neill, Alex J.
Publicado em 2011

“tet(U)” Is Not a Tetracycline Resistance Determinant

Por Caryl, Jamie A., Cox, Georgina, Trimble, Stefan, O'Neill, Alex J.
Publicado em 2012

ABC-F Proteins Mediate Antibiotic Resistance through Ribosomal Protection

Por Sharkey, Liam K. R., Edwards, Thomas A., O’Neill, Alex J.
Publicado no mBio (2016)

Targeting Multiple Aminoacyl-tRNA Synthetases Overcomes the Resistance Liabilities Associated with Antibacterial Inhibitors Acting on a Single Such Enzyme

Por Randall, Christopher P., Rasina, Dace, Jirgensons, Aigars, O'Neill, Alex J.
Publicado no Antimicrob Agents Chemother (2016)

Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections

Por Hurdle, Julian G., O’Neill, Alex J., Chopra, Ian, Lee, Richard E.
Publicado em 2011

The Target of Daptomycin Is Absent from Escherichia coli and Other Gram-Negative Pathogens

Por Randall, Christopher P., Mariner, Katherine R., Chopra, Ian, O'Neill, Alex J.
Publicado em 2013

Further Characterization of Bacillus subtilis Antibiotic Biosensors and Their Use for Antibacterial Mode-of-Action Studies

Por Mariner, Katherine R., Ooi, Nicola, Roebuck, Deborah, O'Neill, Alex J., Chopra, Ian
Publicado em 2011

Silver resistance in Gram-negative bacteria: a dissection of endogenous and exogenous mechanisms

Por Randall, Christopher P., Gupta, Arya, Jackson, Nicole, Busse, David, O'Neill, Alex J.
Publicado no J Antimicrob Chemother (2015)

In vivo transfer of high-level mupirocin resistance from Staphylococcus epidermidis to methicillin-resistant Staphylococcus aureus associated with failure of mupirocin prophylaxis

Por Hurdle, Julian G., O’Neill, Alex J., Mody, Lona, Chopra, Ian, Bradley, Suzanne F.
Publicado em 2005

A target-protection mechanism of antibiotic resistance at atomic resolution: insights into FusB-type fusidic acid resistance

Por Tomlinson, Jennifer H., Thompson, Gary S., Kalverda, Arnout P., Zhuravleva, Anastasia, O’Neill, Alex J.
Publicado no Sci Rep (2016)

Activity of and Development of Resistance to Corallopyronin A, an Inhibitor of RNA Polymerase

Por Mariner, Katherine, McPhillie, Martin, Trowbridge, Rachel, Smith, Catriona, O'Neill, Alex J., Fishwick, Colin W. G., Chopra, Ian
Publicado em 2011

Furanyl-Rhodanines Are Unattractive Drug Candidates for Development as Inhibitors of Bacterial RNA Polymerase

Por Mariner, Katherine R., Trowbridge, Rachel, Agarwal, Anil K., Miller, Keith, O'Neill, Alex J., Fishwick, Colin W. G., Chopra, Ian
Publicado em 2010

Structure-Based Ligand Design of Novel Bacterial RNA Polymerase Inhibitors

Por McPhillie, Martin J., Trowbridge, Rachel, Mariner, Katherine R., O’Neill, Alex J., Johnson, A. Peter, Chopra, Ian, Fishwick, Colin W. G.
Publicado em 2011

A Polymorphism in leuS Confers Reduced Susceptibility to GSK2251052 in a Clinical Isolate of Staphylococcus aureus

Por Gupta, Arya, Monteferrante, Carmine, Rasina, Dace, Leitis, Gundars, Randall, Christopher P., Tomlinson, Jennifer H., Jirgensons, Aigars, Goessens, Wil H. F., Hays, John P., O'Neill, Alex J.
Publicado no Antimicrob Agents Chemother (2016)

6-Arylpyrido[2,3-d]pyrimidines as Novel ATP-Competitive Inhibitors of Bacterial D-Alanine:D-Alanine Ligase

Por Škedelj, Veronika, Arsovska, Emilija, Tomašić, Tihomir, Kroflič, Ana, Hodnik, Vesna, Hrast, Martina, Bešter-Rogač, Marija, Anderluh, Gregor, Gobec, Stanislav, Bostock, Julieanne, Chopra, Ian, O'Neill, Alex J., Randall, Christopher, Zega, Anamarija
Publicado em 2012