Mutagenesis Mapping of the Protein-Protein Interaction Underlying FusB-Type Fusidic Acid Resistance

FusB-type proteins represent the predominant mechanism of resistance to fusidic acid in staphylococci and act by binding to and modulating the function of the drug target (elongation factor G [EF-G]). To gain further insight into this antibiotic resistance mechanism, we sought to identify residues i...

Full description

Saved in:
Bibliographic Details
Main Authors: Cox, Georgina, Edwards, Thomas A., O'Neill, Alex J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811445/
https://ncbi.nlm.nih.gov/pubmed/23836182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00198-13
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items