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A target-protection mechanism of antibiotic resistance at atomic resolution: insights into FusB-type fusidic acid resistance
Antibiotic resistance in clinically important bacteria can be mediated by proteins that physically associate with the drug target and act to protect it from the inhibitory effects of an antibiotic. We present here the first detailed structural characterization of such a target protection mechanism m...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725979/ https://ncbi.nlm.nih.gov/pubmed/26781961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19524 |
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