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Fusidic acid resistance through changes in the dynamics of the drug target

Antibiotic resistance in clinically important bacteria can be mediated by target protection mechanisms, whereby a protein binds to the drug target and protects it from the inhibitory effects of the antibiotic. The most prevalent source of clinical resistance to the antibiotic fusidic acid (FA) is ex...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tomlinson, Jennifer H., Kalverda, Arnout P., Calabrese, Antonio N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568287/
https://ncbi.nlm.nih.gov/pubmed/32999060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008577117
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