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Structure-Based Ligand Design of Novel Bacterial RNA Polymerase Inhibitors
[Image: see text] Bacterial RNA polymerase (RNAP) is essential for transcription and is an antibacterial target for small molecule inhibitors. The binding region of myxopyronin B (MyxB), a bacterial RNAP inhibitor, offers the possibility of new inhibitor design. The molecular design program SPROUT h...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical Society
2011
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| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017976/ https://ncbi.nlm.nih.gov/pubmed/24900260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200087m |
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