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The Target of Daptomycin Is Absent from Escherichia coli and Other Gram-Negative Pathogens

Antistaphylococcal agents commonly lack activity against Gram-negative bacteria like Escherichia coli owing to the permeability barrier presented by the outer membrane and/or the action of efflux transporters. When these intrinsic resistance mechanisms are artificially compromised, such agents almos...

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Détails bibliographiques
Auteurs principaux: Randall, Christopher P., Mariner, Katherine R., Chopra, Ian, O'Neill, Alex J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535891/
https://ncbi.nlm.nih.gov/pubmed/23114759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02005-12
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