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RNA Polymerase Inhibitors with Activity against Rifampin-Resistant Mutants of Staphylococcus aureus

A collection of rifampin-resistant mutants of Staphylococcus aureus with characterized RNA polymerase β-subunit (rpoB) gene mutations was cross-screened against a number of other RNA polymerase inhibitors to correlate susceptibility with specific rpoB genotypes. The rpoB mutants were cross-resistant...

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Detalhes bibliográficos
Main Authors: O'Neill, Alexander, Oliva, Brunello, Storey, Christopher, Hoyle, Anthony, Fishwick, Colin, Chopra, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC101622/
https://ncbi.nlm.nih.gov/pubmed/11036042
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