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Increased Mutability of Staphylococci in Biofilms as a Consequence of Oxidative Stress

OBJECTIVES: To investigate the development of mutational resistance to antibiotics in staphylococcal biofilms. METHODS: Mutation frequencies to resistance against mupirocin and rifampicin were determined for planktonic cultures and for biofilms generated using either a novel static biofilm model or...

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Detalhes bibliográficos
Main Authors: Ryder, Victoria J., Chopra, Ian, O’Neill, Alex J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480535/
https://ncbi.nlm.nih.gov/pubmed/23110091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047695
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