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In Vitro Studies Indicate a High Resistance Potential for the Lantibiotic Nisin in Staphylococcus aureus and Define a Genetic Basis for Nisin Resistance

Lantibiotics such as nisin (NIS) are peptide antibiotics that may have a role in the chemotherapy of bacterial infections. A perceived benefit of lantibiotics for clinical use is their low propensity to select resistance, although detailed resistance studies with relevant bacterial pathogens are lac...

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Detalhes bibliográficos
Main Authors: Blake, Katy L., Randall, Chris P., O'Neill, Alex J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088262/
https://ncbi.nlm.nih.gov/pubmed/21300840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01077-10
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