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Structural basis of lantibiotic recognition by the nisin resistance protein from Streptococcus agalactiae

Lantibiotics are potent antimicrobial peptides. Nisin is the most prominent member and contains five crucial lanthionine rings. Some clinically relevant bacteria express membrane-associated resistance proteins that proteolytically inactivate nisin. However, substrate recognition and specificity of t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Khosa, Sakshi, Frieg, Benedikt, Mulnaes, Daniel, Kleinschrodt, Diana, Hoeppner, Astrid, Gohlke, Holger, Smits, Sander H. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698656/
https://ncbi.nlm.nih.gov/pubmed/26727488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18679
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