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Structural basis of lantibiotic recognition by the nisin resistance protein from Streptococcus agalactiae

Lantibiotics are potent antimicrobial peptides. Nisin is the most prominent member and contains five crucial lanthionine rings. Some clinically relevant bacteria express membrane-associated resistance proteins that proteolytically inactivate nisin. However, substrate recognition and specificity of t...

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書目詳細資料
發表在:Sci Rep
Main Authors: Khosa, Sakshi, Frieg, Benedikt, Mulnaes, Daniel, Kleinschrodt, Diana, Hoeppner, Astrid, Gohlke, Holger, Smits, Sander H. J.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698656/
https://ncbi.nlm.nih.gov/pubmed/26727488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18679
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