Multivariate simulation framework reveals performance of multi-trait GWAS methods

Por Porter, Heather F., O’Reilly, Paul F.
Publicado no Sci Rep (2017)

PRSice-2: Polygenic Risk Score software for biobank-scale data

Por Choi, Shing Wan, O'Reilly, Paul F
Publicado no Gigascience (2019)

Assortative Mating—A Missing Piece in the Jigsaw of Psychiatric Genetics

Por Plomin, Robert, Krapohl, Eva, O’Reilly, Paul F.
Publicado no JAMA Psychiatry (2016)

Confounding between recombination and selection, and the Ped/Pop method for detecting selection

Por O’Reilly, Paul F., Birney, Ewan, Balding, David J.
Publicado em 2008

PRSice: Polygenic Risk Score software

Por Euesden, Jack, Lewis, Cathryn M., O’Reilly, Paul F.
Publicado no Bioinformatics (2015)

A guide to performing Polygenic Risk Score analyses

Por Choi, Shing Wan, Mak, Timothy Shin Heng, O’Reilly, Paul F.
Publicado no Nat Protoc (2020)

The Effect of Genomic Inversions on Estimation of Population Genetic Parameters from SNP Data

Por Seich al Basatena, Nafisa-Katrin, Hoggart, Clive J., Coin, Lachlan J., O’Reilly, Paul F.
Publicado em 2013

Association of Polygenic Risk for Attention-Deficit/Hyperactivity Disorder With Co-occurring Traits and Disorders

Por Du Rietz, Ebba, Coleman, Jonathan, Glanville, Kylie, Choi, Shing Wan, O’Reilly, Paul F., Kuntsi, Jonna
Publicado no Biol Psychiatry Cogn Neurosci Neuroimaging (2018)

Comparing Within- and Between-Family Polygenic Score Prediction

Por Selzam, Saskia, Ritchie, Stuart J., Pingault, Jean-Baptiste, Reynolds, Chandra A., O’Reilly, Paul F., Plomin, Robert
Publicado no Am J Hum Genet (2019)

Co-acting gene networks predict TRAIL responsiveness of tumour cells with high accuracy

Por O’Reilly, Paul, Ortutay, Csaba, Gernon, Grainne, O’Connell, Enda, Seoighe, Cathal, Boyce, Susan, Serrano, Luis, Szegezdi, Eva
Publicado no BMC Genomics (2014)

Fregene: Simulation of realistic sequence-level data in populations and ascertained samples

Por Chadeau-Hyam, Marc, Hoggart, Clive J, O'Reilly, Paul F, Whittaker, John C, De Iorio, Maria, Balding, David J
Publicado em 2008

The Ldb1 and Ldb2 Transcriptional Cofactors Interact with the Ste20-like Kinase SLK and Regulate Cell Migration

Por Storbeck, Chris J., Wagner, Simona, O'Reilly, Paul, McKay, Marlene, Parks, Robin J., Westphal, Heiner, Sabourin, Luc A.
Publicado em 2009

Investigating the effects of genetic risk of schizophrenia on behavioural traits

Por Socrates, Adam, Maxwell, Jessye, Glanville, Kylie P., Di Forti, Marta, Murray, Robin M., Vassos, Evangelos, O’Reilly, Paul F.
Publicado no NPJ Schizophr (2021)

Connectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapies

Por Wen, Qing, O'Reilly, Paul, Dunne, Philip D, Lawler, Mark, Van Schaeybroeck, Sandra, Salto-Tellez, Manuel, Hamilton, Peter, Zhang, Shu-Dong
Publicado no BMC Syst Biol (2015)

Genome-Wide Polygenic Scores Predict Reading Performance Throughout the School Years

Por Selzam, Saskia, Dale, Philip S., Wagner, Richard K., DeFries, John C., Cederlöf, Martin, O’Reilly, Paul F., Krapohl, Eva, Plomin, Robert
Publicado no Sci Stud Read (2017)

Evidence for gene-environment correlation in child feeding: Links between common genetic variation for BMI in children and parental feeding practices

Por Selzam, Saskia, McAdams, Tom A., Coleman, Jonathan R. I., Carnell, Susan, O’Reilly, Paul F., Plomin, Robert, Llewellyn, Clare H.
Publicado no PLoS Genet (2018)

Translational AI and Deep Learning in Diagnostic Pathology

Por Serag, Ahmed, Ion-Margineanu, Adrian, Qureshi, Hammad, McMillan, Ryan, Saint Martin, Marie-Judith, Diamond, Jim, O'Reilly, Paul, Hamilton, Peter
Publicado no Front Med (Lausanne) (2019)

MultiPhen: Joint Model of Multiple Phenotypes Can Increase Discovery in GWAS

Por O’Reilly, Paul F., Hoggart, Clive J., Pomyen, Yotsawat, Calboli, Federico C. F., Elliott, Paul, Jarvelin, Marjo-Riitta, Coin, Lachlan J. M.
Publicado em 2012

Fine-Scale Estimation of Location of Birth from Genome-Wide Single-Nucleotide Polymorphism Data

Por Hoggart, Clive J., O’Reilly, Paul F., Kaakinen, Marika, Zhang, Weihua, Chambers, John C., Kooner, Jaspal S., Coin, Lachlan J. M., Jarvelin, Marjo-Riitta
Publicado em 2012

KRAS mutant colorectal cancer gene signatures identified angiotensin II receptor blockers as potential therapies

Por Wen, Qing, Dunne, Philip D., O’Reilly, Paul G., Li, Gerald, Bjourson, Anthony J., McArt, Darragh G., Hamilton, Peter W., Zhang, Shu-Dong
Publicado no Oncotarget (2016)