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MultiPhen: Joint Model of Multiple Phenotypes Can Increase Discovery in GWAS
The genome-wide association study (GWAS) approach has discovered hundreds of genetic variants associated with diseases and quantitative traits. However, despite clinical overlap and statistical correlation between many phenotypes, GWAS are generally performed one-phenotype-at-a-time. Here we compare...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3342314/ https://ncbi.nlm.nih.gov/pubmed/22567092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034861 |
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