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PRSice: Polygenic Risk Score software

Summary: A polygenic risk score (PRS) is a sum of trait-associated alleles across many genetic loci, typically weighted by effect sizes estimated from a genome-wide association study. The application of PRS has grown in recent years as their utility for detecting shared genetic aetiology among trait...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Euesden, Jack, Lewis, Cathryn M., O’Reilly, Paul F.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410663/
https://ncbi.nlm.nih.gov/pubmed/25550326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu848
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