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Prospects for using risk scores in polygenic medicine
Genome-wide association studies have made strides in identifying common variation associated with disease. The modest effect sizes preclude risk prediction based on single genetic variants, but polygenic risk scores that combine thousands of variants show some predictive ability across a range of co...
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| Gepubliceerd in: | Genome Med |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5683372/ https://ncbi.nlm.nih.gov/pubmed/29132412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0489-y |
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