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Polygenic risk scores: from research tools to clinical instruments

Genome-wide association studies have shown unequivocally that common complex disorders have a polygenic genetic architecture and have enabled researchers to identify genetic variants associated with diseases. These variants can be combined into a polygenic risk score that captures part of an individ...

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Detalles Bibliográficos
Publicado en:Genome Med
Main Authors: Lewis, Cathryn M., Vassos, Evangelos
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236300/
https://ncbi.nlm.nih.gov/pubmed/32423490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00742-5
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