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A guide to performing Polygenic Risk Score analyses

The application of polygenic risk scores (PRS) has become routine across biomedical research. Among a range of applications, PRS are exploited to assess shared aetiology between phenotypes, to evaluate the clinical utility of genetic data for common disease, and as part of experimental studies in wh...

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Podrobná bibliografie
Vydáno v:Nat Protoc
Hlavní autoři: Choi, Shing Wan, Mak, Timothy Shin Heng, O’Reilly, Paul F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612115/
https://ncbi.nlm.nih.gov/pubmed/32709988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-020-0353-1
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