Fregene: Simulation of realistic sequence-level data in populations and ascertained samples

BACKGROUND: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows complex scenarios of selection, demography, and recombination to be modelled simultaneously. Detailed tracking of sites...

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Hlavní autoři: Chadeau-Hyam, Marc, Hoggart, Clive J, O'Reilly, Paul F, Whittaker, John C, De Iorio, Maria, Balding, David J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Software
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542380/
https://ncbi.nlm.nih.gov/pubmed/18778480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-364
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