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Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies

Testing one SNP at a time does not fully realise the potential of genome-wide association studies to identify multiple causal variants, which is a plausible scenario for many complex diseases. We show that simultaneous analysis of the entire set of SNPs from a genome-wide study to identify the subse...

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Detalhes bibliográficos
Main Authors: Hoggart, Clive J., Whittaker, John C., De Iorio, Maria, Balding, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464715/
https://ncbi.nlm.nih.gov/pubmed/18654633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000130
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