All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs

Recent results indicate that genome-wide association studies (GWAS) have the potential to explain much of the heritability of common complex phenotypes, but methods are lacking to reliably identify the remaining associated single nucleotide polymorphisms (SNPs). We applied stratified False Discovery...

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Detalhes bibliográficos
Main Authors: Schork, Andrew J., Thompson, Wesley K., Pham, Phillip, Torkamani, Ali, Roddey, J. Cooper, Sullivan, Patrick F., Kelsoe, John R., O'Donovan, Michael C., Furberg, Helena, Schork, Nicholas J., Andreassen, Ole A., Dale, Anders M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636284/
https://ncbi.nlm.nih.gov/pubmed/23637621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003449
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